BDBM50636832 CHEMBL5560466

SMILES C=CC(=O)N1C[C@@H](n2cc(-c3ccncc3)c(-c3cc(COc4ccc5c(c4)CN(C)C5=O)ccc3F)n2)C[C@H]1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50636832   

TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636832(CHEMBL5560466)
Affinity DataIC50: 90nMAssay Description:Inhibition of EGFR D770_N771insSVD mutant (unknown origin) phosphorylation transfected in human NCI-H2073 cells incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636832(CHEMBL5560466)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) phosphorylation transfected in human NCI-H2073 cells preincubated for 2 hrs followed by EGF stimulation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed