BDBM50637113 CHEMBL5563550

SMILES Cn1cc2c(n1)c(=O)n(-c1cccnc1)c1nc(Cl)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50637113   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637113(CHEMBL5563550)
Affinity DataIC50: 40nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637113(CHEMBL5563550)
Affinity DataIC50: 254nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed