BDBM50637406 CHEMBL4744680

SMILES O=C(N[C@@H](C1CC1)C(F)(F)F)c1cc(-c2cnn3cc(-c4ccc(F)cc4)cnc23)cs1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50637406   

TargetSerine/threonine-protein kinase ULK1(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human ULK1 by discoverX kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human ULK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant DRAK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant MNK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK2(Human)
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 30nMAssay Description:Inhibition of human ULK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK2(Human)
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 30nMAssay Description:Inhibition of human ULK2 by discoverX kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataEC50:  390nMAssay Description:Inhibition of ULK1 phosphorylation at Ser15 residue in HEK293 cells incubated for 1 hr by chemiluminescence based immunoblotting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed