BDBM50637582 CHEMBL5555976

SMILES COc1cc2nc(C)c3nc(C)n(Cc4ccc(S(N)(=O)=O)cn4)c3c2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50637582   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637582(CHEMBL5555976)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of human ENPP1 using TMP-pNP as substrate at pH 9.5 preincubated for 30 mins followed by substrate addition and measured after 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637582(CHEMBL5555976)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human ENPP1 using AMP-pNP as substrate at pH 9.5 preincubated for 30 mins followed by substrate addition and measured after 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637582(CHEMBL5555976)
Affinity DataIC50: 400nMAssay Description:Inhibition of ENPP1 (unknown origin) expressed in human MDA-MB-231 cells using TMP-pNP as substrate preincubated for 60 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed