BDBM50637907 CHEMBL5532457

SMILES Cc1cc(C)cc(Nc2nccc(-c3cc(C(=O)NCC(F)(F)F)n(C)n3)n2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50637907   

TargetTyrosine-protein kinase SYK(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637907(CHEMBL5532457)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human N-terminal His/GST-tagged SYK (356 to 635 residues) expressed in baculovirus infected Sf21 cells using KKKKKEQE-DEPEG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637907(CHEMBL5532457)
Affinity DataIC50: 692nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 60 mins in presence of ATP by KinaseGlo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637907(CHEMBL5532457)
Affinity DataIC50: 704nMAssay Description:Inhibition of FLT3 (unknown origin) incubated for 60 mins in presence of ATP by KinaseGlo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637907(CHEMBL5532457)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of LYN (unknown origin) incubated for 60 mins in presence of ATP by KinaseGlo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed