BDBM50637929 CHEMBL5555133

SMILES C[C@@H](CN1CCC1)NC(=O)c1cc(-c2ccnc(Nc3cccc(C#N)c3)n2)nn1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50637929   

TargetTyrosine-protein kinase SYK(Human)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637929(CHEMBL5555133)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human N-terminal His/GST-tagged SYK (356 to 635 residues) expressed in baculovirus infected Sf21 cells using KKKKKEQE-DEPEG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Mus musculus)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637929(CHEMBL5555133)
Affinity DataIC50: 69nMAssay Description:Inhibition of SYK in mouse BaF3-TEL/SYK cells in absence of IL-3 stimulationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Mus musculus)
Nerviano Medical Sciences S.r.l.

Curated by ChEMBL
LigandPNGBDBM50637929(CHEMBL5555133)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYK in IL-3 stimulated mouse BaF3-TEL/SYK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed