BDBM50638205 CHEMBL5549898

SMILES CN(C(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@@H](NC(=O)c1cccs1)C(C)(C)C)N(C#N)Cc1cccc(Cl)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50638205   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50638205(CHEMBL5549898)
Affinity DataIC50: 4nMAssay Description:Inhibition of SARS-CoV2 main protease using Boc-Abu-Tle-Leu-Gln-AMC as substrate preincubated for 5 mins followed by enzyme addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50638205(CHEMBL5549898)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant human cathepsin S using Z-Phe-Arg-AMC as substrate incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50638205(CHEMBL5549898)
Affinity DataKi:  98nMAssay Description:Inhibition of cathepsin B (unknown origin) using Z-Arg-Arg-pNA as substrate incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50638205(CHEMBL5549898)
Affinity DataKi:  178nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA as substrate incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed