BDBM50638256 CHEMBL5561438

SMILES O=P(O)(O)C(F)(F)c1cccc2oc3ccccc3c12

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50638256   

TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataKi:  5.80E+3nMAssay Description:Competitive inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein phosphatase CDC14B(Homo sapiens)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataKi:  7.30E+3nMAssay Description:Competitive inhibition of human CDC14B using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 9.85E+3nMAssay Description:Inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein phosphatase CDC14B(Homo sapiens)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human CDC14B using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 2.05E+5nMAssay Description:Inhibition of laforin (1 to 331 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein phosphatase 10(Mus musculus)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of mouse MKP-5 (320 to 647 residues) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluorescen...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase C(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of CD45 (620 to 1236 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of LYP (1 to 294 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluo...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B (1 to 321 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by f...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of FAP-1 (2124 to 2485 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins b...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of SHP-1 (245 to 543 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of SHP-2 (224 to 528 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of STEP (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50638256(CHEMBL5561438)Copy SMILES

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of TCPTP (1 to 387 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL