BDBM50638257 CHEMBL5567968

SMILES C=C(c1ccccc1)c1ccc(C(F)(F)P(=O)(O)O)c2c1oc1ccccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50638257   

TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataKi:  57nMAssay Description:Reversible competitive inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 90nMAssay Description:Inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14B(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataKi:  90nMAssay Description:Reversible competitive inhibition of human CDC14B using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 93nMAssay Description:Inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Mus musculus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of mouse MKP-5 (320 to 647 residues) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLaforin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of laforin (1 to 331 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of FAP-1 (2124 to 2485 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of SHP-1 (245 to 543 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of SHP-2 (224 to 528 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of HePTP (22 to 360 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of LYP (1 to 294 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of STEP (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase 23(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of VHZ (1 to 150 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of CD45 (620 to 1236 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of PTP1B (1 to 321 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 6.84E+4nMAssay Description:Inhibition of LMPTP (1 to 158 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 7.95E+4nMAssay Description:Inhibition of TCPTP (1 to 387 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PEST (5 to 304 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTP-epsilon (107 to 697 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTP-alpha (173 to 793 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed