BDBM50638326 CHEMBL4476393

SMILES O=S(=O)(Nc1ccc2c(c1)CCN2Cc1ccc(C(F)(F)F)cc1C(F)(F)F)C1CCCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50638326   

TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 210nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human KCNT2 expressed in HEK cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed