BDBM50638327 CHEMBL5558981

SMILES CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50638327   

TargetToll-like receptor 7(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50638327(CHEMBL5558981)
Affinity DataEC50:  202nMAssay Description:Agonist activity at human TLR7 expressed in HEK-blue TLR cells measured for 18 to 19 hrs by SEAP reporter gene based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetToll-like receptor 7(Mouse)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50638327(CHEMBL5558981)
Affinity DataEC50:  299nMAssay Description:Agonist activity at mouse TLR7 expressed in HEK293 cells co-expressing NF-kappaB/AP-1 inducible SEAP reporter gene measured for 24 hrs by colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50638327(CHEMBL5558981)
Affinity DataEC50:  1.06E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK-blue TLR cells measured for 18 to 19 hrs by SEAP reporter gene based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50638327(CHEMBL5558981)
Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed