BDBM50638376 CHEMBL5555317

SMILES Cc1ncsc1-c1ccc([C@@H](C)NC(=O)[C@H]2C[C@H](O)CN2C(=O)[C@H](NC(=O)COCCOCCOCCOc2ccc(N(CC(F)(F)F)S(=O)(=O)C3CC4OC3C(c3ccc(-n5ccnc5)cc3)=C4c3ccc(O)cc3)cc2)C(C)(C)C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50638376   

TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandPNGBDBM50638376(CHEMBL5555317)
Affinity DataKi:  78nMAssay Description:Binding affinity to human ERalpha assessed as inhibition constant incubated under dark condition for 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandPNGBDBM50638376(CHEMBL5555317)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to human ERbeta assessed as inhibition constant incubated under dark condition for 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandPNGBDBM50638376(CHEMBL5555317)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human aromatase using ARO substrate/NADP+ mixture by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed