BDBM50639064 CHEMBL5556843

SMILES CNC(=O)c1cc2nccc(N)c2[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639064   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50639064(CHEMBL5556843)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of recombinant C-terminal truncated human SHP2 (1 to 530 residues) using 6,8-difluoro-4-methylumbelliferyl phosphate as substrate and H2N-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50639064(CHEMBL5556843)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to C-terminal 6His tagged full length SHP2 (1 to 528 residues) (unknown origin) transfected in Escherichia coli BL21(DE3) RIPL cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed