BDBM50639141 CHEMBL5555137

SMILES C[C@@H]1CN(Cc2ccc(C(=O)O)cc2)[C@H](C)CN1Cc1ccc(Oc2ccc(-c3ncco3)cc2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50639141   

TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639141(CHEMBL5555137)
Affinity DataIC50: 3nMAssay Description:Inhibition of LTA4H (unknown origin) using Arg-AMC as substrate preincubated with compound for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639141(CHEMBL5555137)
Affinity DataIC50: 135nMAssay Description:Inhibition of LTA4H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639141(CHEMBL5555137)
Affinity DataIC50: 140nMAssay Description:Inhibition of LTA4H in human whole blood assessed as calcium ionophore A23187-stimulated LTB4 release preincubated with compound for 4 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed