BDBM50639154 CHEMBL5558287

SMILES c1cc(-c2ccc(Oc3ccc(CN4CCCC4)nc3)nc2)[nH]n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639154   

TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639154(CHEMBL5558287)
Affinity DataIC50: 6nMAssay Description:Inhibition of LTA4H (unknown origin) using Arg-AMC as substrate preincubated with compound for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639154(CHEMBL5558287)
Affinity DataIC50: 49nMAssay Description:Inhibition of LTA4H in human whole blood assessed as calcium ionophore A23187-stimulated LTB4 release preincubated with compound for 4 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed