BDBM50639155 CHEMBL5560265

SMILES c1cc(-c2ccc(Oc3ccc(CN4CCCCC4)nc3)nc2)[nH]n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639155   

TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639155(CHEMBL5560265)
Affinity DataIC50: 3nMAssay Description:Inhibition of LTA4H (unknown origin) using Arg-AMC as substrate preincubated with compound for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50639155(CHEMBL5560265)
Affinity DataIC50: 67nMAssay Description:Inhibition of LTA4H in human whole blood assessed as calcium ionophore A23187-stimulated LTB4 release preincubated with compound for 4 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed