BDBM50639176 CHEMBL5560759

SMILES CC(=O)N[C@H]1Cc2ccc(cc2)OCCCC[C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)c2nc3ccccc3s2)NC(=O)[C@H](CC(C)C)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50639176   

TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant hepsin (Arg45 to Leu417 residues) using Boc-QAR-AMC as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant TMPRSS2 (106 to 492 residues) using Boc-QAR-AMC as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal Met/6His tagged human recombinant matriptase catalytic domain (Gly596 to Val855 residues) using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 40nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProthrombin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as chromogenic substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of factor Xa (unknown origin) using Bz-lle-Glu-Gly-Arg-pNA as chromogenic substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed