BDBM50639184 CHEMBL5557551
SMILES CC(=O)N[C@H]1Cc2ccc(cc2)Oc2ccc(cc2)C[C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)c2nc3ccccc3s2)NC(=O)[C@H](CC(C)C)NC1=O
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50639184
TargetTransmembrane protease serine 2(Human)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant TMPRSS2 (106 to 492 residues) using Boc-QAR-AMC as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant hepsin (Arg45 to Leu417 residues) using Boc-QAR-AMC as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of N-terminal Met/6His tagged human recombinant matriptase catalytic domain (Gly596 to Val855 residues) using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Human)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair