BDBM50639228 CHEMBL5561839

SMILES CC(C)n1nnc2ccc(-c3ccnc(Nc4cc(C(=O)N5CCCC5)ccn4)c3)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50639228   

TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) using PDKtide substrate incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 36nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 134nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 161nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639228(CHEMBL5561839)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed