BDBM50639351 CHEMBL5543021

SMILES CN1CCC(NC(=O)[C@H]2CC[C@H](NC(=O)c3cnc4nc3Nc3ccc(F)c(c3)OC/C=C\CN4)CC2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50639351   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50639351(CHEMBL5543021)
Affinity DataIC50: 3nMAssay Description:Inhibition of MERTK (unknown origin) expressed in HEK293 cells by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50639351(CHEMBL5543021)
Affinity DataIC50: 11nMAssay Description:Inhibition of FLT3 (unknown origin) by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50639351(CHEMBL5543021)
Affinity DataIC50: 14nMAssay Description:Inhibition of AXL (unknown origin) by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50639351(CHEMBL5543021)
Affinity DataIC50: 200nMAssay Description:Inhibition of TYRO3 (unknown origin) by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed