BDBM50639388 CHEMBL5542106

SMILES COc1cccc(Nc2nccc(N3CCCn4nc(C#CC(C)(O)c5nccs5)cc43)n2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50639388   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639388(CHEMBL5542106)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of NIK (unknown origin) incubated 30 to 60 mins by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639388(CHEMBL5542106)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of NIK (unknown origin) incubated 30 to 60 mins by ADP-Glo KinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639388(CHEMBL5542106)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of NIK (unknown origin) expressed in COS-7 cells co-expressing NF-KappaB luciferase reporter assessed as suppression of luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed