BDBM50639586 CHEMBL5560793

SMILES CN1CCN(CC2CCc3c(c4cc(F)ccc4n3Cc3ccc(C(=O)NO)cc3)C2=O)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50639586   

TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant HDAC6 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HDAC6 expressed in Spodoptera frugiperda incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human recombinant HDAC8 using fluorescent peptide p53 (379 to 382 residues) (RHK(Ac)K(Ac)) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human recombinant HDAC9 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of his-tagged human recombinant HDAC1 using fluor de lys-SIRT1 as substrate incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human recombinant HDAC5 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of human recombinant HDAC7 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human recombinant HDAC11 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant HDAC1 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC10 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639586(CHEMBL5560793)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC3 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed