BDBM50639594 CHEMBL5555202

SMILES CC1(C)CC(=O)c2c(C(F)(F)F)nn(Cc3ccc(C(=O)NO)cc3)c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50639594   

TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HDAC6 expressed in Spodoptera frugiperda incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC6 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of his-tagged human recombinant HDAC1 using fluor de lys-SIRT1 as substrate incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 4.99E+3nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of human recombinant HDAC5 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of human recombinant HDAC9 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC7 using Boc-Lys(tri-fluoroacetyl)-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC10 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC11 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC3 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 using fluorescent peptide p53 (379 to 382 residues) (RHK(Ac)K(Ac)) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50639594(CHEMBL5555202)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed