BDBM50639625 CHEMBL5565693

SMILES C=CC(=O)N1CCN(c2nc(N3CC(N(C)C)C3)nc3c2C[C@@H](C)[C@H](c2c(Cl)c(C)cc4[nH]ccc24)C3)C[C@H]1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639625   

TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639625(CHEMBL5565693)
Affinity DataIC50: 60nMAssay Description:Inhibition of KRAS G12C mutant in human MIA PaCa-2 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639625(CHEMBL5565693)
Affinity DataIC50: 64nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed