BDBM50639626 CHEMBL5531972

SMILES C=CC(=O)N1CCN(c2nc(N3CC(N(C)C)C3)nc3c2C[C@@H](C)C(c2c(C)c(Cl)cc4[nH]ncc24)C3)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639626   

TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639626(CHEMBL5531972)
Affinity DataIC50: 68nMAssay Description:Inhibition of KRAS G12C mutant in human MIA PaCa-2 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639626(CHEMBL5531972)
Affinity DataIC50: 102nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed