BDBM50639627 CHEMBL5561896

SMILES C=CC(=O)N1CCN(c2nc(O[C@@H]3CN(C)C[C@H]3OC)nc3c(Oc4c(Cl)c(Cl)cc5[nH]ncc45)nc(Cl)cc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50639627   

TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639627(CHEMBL5561896)
Affinity DataIC50: 5nMAssay Description:Inhibition of GDP-bound KRAS G12C mutant in human MIA PaCa-2 cells incubated for 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed