BDBM50639758 CHEMBL5542292

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(C4(N(CC)C(C)C)COC4)c(F)c3)c3c(N)ncnc3n2C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50639758   

TargetFibroblast growth factor receptor 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50639758(CHEMBL5542292)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of N-terminal His6-tagged FGFR2 (458 to 768 residues)(unknown origin) expressed in Escherichia coli BL21 (DE3) using Peptide30 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50639758(CHEMBL5542292)
Affinity DataIC50: 180nMAssay Description:Inhibition of FGFR3 (unknown origin) using Peptide30 as substrate incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50639758(CHEMBL5542292)
Affinity DataIC50: 319nMAssay Description:Inhibition of FGFR1 (unknown origin) using Peptide30 as substrate incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50639758(CHEMBL5542292)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of FGFR4 (unknown origin) using Peptide30 as substrate incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed