BDBM50639816 CHEMBL5561243

SMILES COc1cc(NC(=O)c2cc(=O)c3ccccc3o2)c(C(=O)Nc2ccc(C3CCN(Cc4cccc(-c5cccnc5)c4)CC3)cc2)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639816   

TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50639816(CHEMBL5561243)
Affinity DataEC50:  65nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50639816(CHEMBL5561243)
Affinity DataEC50:  232nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed