BDBM50639862 CHEMBL5567650

SMILES CN(C)c1cccc([C@H](N)CN(C)S(=O)(=O)c2cc(F)cc(F)c2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639862   

TargetLysosomal acid glucosylceramidase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50639862(CHEMBL5567650)
Affinity DataKd:  19nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50639862(CHEMBL5567650)
Affinity DataEC50:  3.71E+4nMAssay Description:Positive allosteric modulation of GCase in human Fibroblast cells using GBA1-FQ2 as substrate preincubated for 24 hrs followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed