BDBM50640085 CHEMBL5556385

SMILES CN(C)CCNC=C1C(=O)CC(c2c(Cl)c(Cl)cc3[nH]ccc23)CC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50640085   

TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of GST-tagged LC3B (unknown origin) using biotin-labeled LBP2 as substrate preincubated with compound for 12 hrs followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 17nMAssay Description:Inhibition of GST-tagged wild type LC3B (unknown origin) using biotin-labeled LBP2 as substrate preincubated with compound for 12 hrs followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 17nMAssay Description:Inhibition of LC3B (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 33nMAssay Description:Inhibition of LC3A (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 56nMAssay Description:Inhibition of GST-tagged LC3B K49R mutant (unknown origin) using biotin-labeled LBP2 as substrate preincubated with compound for 12 hrs followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal GST-tagged LC3B (unknown origin) measured for 18 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor-associated protein-like 2(Homo sapiens)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 860nMAssay Description:Inhibition of GABARAPL2 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor-associated protein-like 1(Homo sapiens)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of GABARAPL1 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGABA(A) receptor-associated protein(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of GABARAP (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated protein 1 light chain 3 gamma(Homo sapiens)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of LC3C (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50640085(CHEMBL5556385)
Affinity DataKi:  9.07E+3nMAssay Description:Binding affinity to N-terminal GST-tagged LC3B (unknown origin) assessed as inhibition constant measured for 18 hrs by fluorescence polarization assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed