BDBM50640212 CHEMBL5566068

SMILES CC1(N)CCN(C(=O)c2ccc(Sc3cccc(Cl)c3Cl)o2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640212   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640212(CHEMBL5566068)
Affinity DataKd:  0.0960nMAssay Description:Inhibition of full length 6His-tagged wild type recombinant human SHP2 assessed as dissociation constant at 2 uM by Grating-Coupled InterferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640212(CHEMBL5566068)
Affinity DataKd:  290nMAssay Description:Inhibition of full length 6His-tagged wild type recombinant human SHP2 assessed as equilibrium dissociation constant at 2 uM by Grating-Coupled Inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640212(CHEMBL5566068)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length 6His-tagged wild type recombinant human SHP2 transfected in Escherichia coli BL21 Star (DE3) cells using DiFMUP as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed