BDBM50640217 CHEMBL5568422

SMILES O=C(c1cc(=O)[nH]c2ccccc12)N1CCN(c2ccc(Cl)c(Cl)c2)CC1CN1CCOCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640217   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50640217(CHEMBL5568422)
Affinity DataKd:  117nMAssay Description:Binding affinity to biotinylated SARS-CoV-2 3CLpro assessed as steady state dissociation constant incubated for 100 sec by biolayer interferometry an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50640217(CHEMBL5568422)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli using MCA-AVLQSGFR-Lys(DNP)-Lys-NH2 as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50640217(CHEMBL5568422)
Affinity DataIC50: 150nMAssay Description:Inhibition of SARS-CoV-2 3CLproMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed