BDBM50640307 CHEMBL5566074

SMILES Oc1ccc(CCC2CCC(c3ccc(O)cc3)CO2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640307   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil preincubated with compound for 15 mins followed by A23187 addition measured after 10 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil using arachidonic acid as substrate preincubated with compound for 15 mins followed by substrate and A23187 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate preincubated with compound for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed