BDBM50640316 CHEMBL5556746

SMILES Cc1[nH]c(/C=C2\C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccc(F)cc4)cc32)c(C)c1NC(=O)[C@H](C)O

InChI Key InChIKey=QPXLZMVVZPIUBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50640316   

TargetG protein-coupled receptor kinase 5(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50640316(CHEMBL5556746)
Affinity DataIC50: 40nMAssay Description:Inhibition of human GRK5 (1 to 590) expressed in Escherichia coli using tubulin as substrate incubated for 5 mins in presence of [gamma-32P]-ATP by r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50640316(CHEMBL5556746)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK2 expressed in baculovirus infected insect cell using tubulin as substrate incubated for 5 mins in presence of [gamma-32P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed