BDBM50640567 CHEMBL5573754::US20250353856, Compound 11

SMILES c1ccc(-c2cc3c(NC4CCOCC4)ncnc3[nH]2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640567   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640567BDBM50640567(CHEMBL5573754 | US20250353856, Compound 11)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640567BDBM50640567(CHEMBL5573754 | US20250353856, Compound 11)
Affinity DataIC50: 60nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640567BDBM50640567(CHEMBL5573754 | US20250353856, Compound 11)
Affinity DataIC50: 99nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed