BDBM50640600 CHEMBL5594111::US20250353856, Compound 12

SMILES c1nc(NC2CCOCC2)c2cc(-c3ccc(CN4CCOCC4)cc3)[nH]c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640600   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640600BDBM50640600(CHEMBL5594111 | US20250353856, Compound 12)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640600BDBM50640600(CHEMBL5594111 | US20250353856, Compound 12)
Affinity DataIC50: 14nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50640600BDBM50640600(CHEMBL5594111 | US20250353856, Compound 12)
Affinity DataIC50: 236nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed