BDBM50640615 CHEMBL5570230

SMILES Cc1nn(CC2CC2)c(C)c1-c1cncc(-c2ccnc3nc[nH]c23)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50640615   

TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 176nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 183nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataKd:  230nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) at 1:1 protein:compound ratio by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 498nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataKd:  540nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of BRDT BD2 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of BRDT BD1 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 15 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) at 1:1 protein:compound ratio by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640615(CHEMBL5570230)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed