BDBM50640760 CHEMBL5572940
SMILES CCS(=O)(=O)Nc1cc(-c2cc(NC3CN(S(=O)(=O)CC)C3)c(=O)n(C)c2)cc2c1ccn2C(C)(c1ccccn1)c1ccccn1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50640760
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataKd: 46nMAssay Description:Binding affinity to his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells assessed as dissociation ...More data for this Ligand-Target Pair
Affinity DataKd: 125nMAssay Description:Binding affinity to his-tagged human BRD4 BD2 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 298nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD2 incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
