BDBM50640776 CHEMBL5556841

SMILES C=CC(=O)N1CC(Oc2nn(C(C)(C)C)c3ncnc(N)c23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50640776   

TargetTyrosine-protein kinase JAK3(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 59nMAssay Description:Inhibition of JAK3 (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 105nMAssay Description:Inhibition of BTK (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 242nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 796nMAssay Description:Inhibition of BLK (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 865nMAssay Description:Displacement of K-10 tracer from wild type BTK in HEK293T cells expressing NanoLuc preincubated for 3 hrs followed by tracer addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 3.43E+3nMAssay Description:Displacement of K-4 tracer from wild type BLK in HEK293T cells expressing NanoLuc preincubated for 3 hrs followed by tracer addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of HER2 (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640776(CHEMBL5556841)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK5 (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed