BDBM50640861 CHEMBL5574816

SMILES Cc1cnc(Nc2ccc(NS(C)(=O)=O)cc2)nc1-c1cnn(C(CC#N)C2CCCC2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50640861   

TargetTyrosine-protein kinase JAK2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50640861(CHEMBL5574816)
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 90 mins in presence of ATP by fluorescence microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50640861(CHEMBL5574816)
Affinity DataIC50: 607nMAssay Description:Inhibition of N-terminal GST-tagged full-length human CDK2(1 to 298 residues) /FLAG-tagged human Cyclin E1 (1 to 410 residues) expressed in baculovir...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed