BDBM50641060 CHEMBL5569778

SMILES COc1ccccc1Nc1nc(-c2cnc3ccccn23)cs1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641060   

TargetPyruvate kinase PKM(Human)TBA
LigandPNGBDBM50641060(CHEMBL5569778)
Affinity DataKd:  0.915nMAssay Description:Binding affinity to human PKM2 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)TBA
LigandPNGBDBM50641060(CHEMBL5569778)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human PKM2 expressed in Escherichia coli preincubated for 30 mins followed by beta-NADH addition and measured over 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed