BDBM50641235 CHEMBL5569466

SMILES O=C(O)c1ccc(-c2nn(C(=O)c3ccccc3C(F)(F)F)c3ccccc23)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50641235   

TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641235(CHEMBL5569466)
Affinity DataKi:  50nMAssay Description:Allosteric inhibition of N-terminal his6-tagged human recombinant RORgamma LBD (261 to 518 residues) expressed in Sf9 insect cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641235(CHEMBL5569466)
Affinity DataIC50: 94nMAssay Description:Allosteric inhibition of N-terminal his6-tagged human recombinant RORgamma LBD (261 to 518 residues) expressed in Sf9 insect cells incubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641235(CHEMBL5569466)
Affinity DataIC50: 98nMAssay Description:Allosteric inhibition of human RORgamma LBD expressed in Escherichia coli BL21 (DE3) cells incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed