BDBM50641293 CHEMBL5563972

SMILES Cn1cc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)Nc3cc(C(C)(C)C)on3)cc2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50641293   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641293(CHEMBL5563972)
Affinity DataIC50: 1nMAssay Description:Inhibition of RET V804M mutant (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641293(CHEMBL5563972)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) expressed in baculovirus infected insect cells using biotinylated-GGGGQDGKDYIVLPI peptide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641293(CHEMBL5563972)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type human RET by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50641293(CHEMBL5563972)
Affinity DataIC50: 1nMAssay Description:Inhibition of 5FAM-tagged RET (unknown origin) using 5FAM-EPLYWSFPA as substrate incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas for Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50641293(CHEMBL5563972)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TRK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed