BDBM50641324 CHEMBL5595401

SMILES O=C(c1cccc(O)c1)N1CCC(Cc2cccc(Sc3cc(C(F)(F)F)ccn3)c2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641324   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50641324(CHEMBL5595401)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50641324(CHEMBL5595401)
Affinity DataIC50: 197nMAssay Description:Reversible inhibition of MAGL in human U-937 cells using 2-oleoylglycerol as substrate preincubated with compound for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed