BDBM50641346 CHEMBL5555399

SMILES O=C(NO)c1ccc(Cn2cnc3c(Nc4ccc(F)c(Cl)c4)ncnc32)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50641346   

TargetHistone deacetylase 1(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641346(CHEMBL5555399)
Affinity DataIC50: 189nMAssay Description:Inhibition of full-length recombinant human HDAC1 expressed in baculovirus infected Sf9 cells using RHKK(Ac)AMC as substrate preincubated for 5 to 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641346(CHEMBL5555399)
Affinity DataIC50: 341nMAssay Description:Inhibition of full-length recombinant human HDAC6 expressed in baculovirus infected Sf9 cells using RHKK(Ac)AMC as substrate preincubated for 5 to 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641346(CHEMBL5555399)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) in presence of ATP by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641346(CHEMBL5555399)
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 30 mins followed by ATP addition measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed