BDBM50641452 CHEMBL5570544

SMILES O=C1NCCc2cccc(c2)Nc2nc(c3ccccc3n2)Nc2cc1[nH]n2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50641452   

TargetSerine/threonine-protein kinase 24(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  920nMAssay Description:Binding affinity to C-terminal full length human MST3 expressed in permeabilized HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  2.44E+3nMAssay Description:Binding affinity to C-terminal full length human MST4 expressed in permeabilized HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  6.51E+3nMAssay Description:Binding affinity to C-terminal full length human MST3 expressed in intact HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  1.18E+4nMAssay Description:Binding affinity to C-terminal full length human MST4 expressed in intact HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  1.30E+4nMAssay Description:Binding affinity to N-terminal full length human MST2 expressed in intact HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641452(CHEMBL5570544)
Affinity DataEC50:  1.37E+4nMAssay Description:Binding affinity to N-terminal full length human MST1 expressed in intact HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed