BDBM50641582 CHEMBL5572105

SMILES CC1=CC[C@@H]2C[C@H]1[C@H](c1ccc(C(F)(F)F)cc1)NC2(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50641582   

TargetSigma intracellular receptor 2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-epibatidine from sigma2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataIC50: 340nMAssay Description:Inhibition of epibatidine-induced receptor activation at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as reduction in calcium flux preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataIC50: 560nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-epibatidine from dopamine transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-epibatidine from M2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-epibatidine from M4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]-epibatidine from sigma1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataIC50: 2.99E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641582(CHEMBL5572105)
Affinity DataIC50: 8.48E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed