BDBM50641585 CHEMBL5571457

SMILES CC1=CC[C@@H]2C[C@H]1[C@H](c1ccc(C(F)(F)F)c(F)c1)NC2(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50641585   

TargetSigma intracellular receptor 2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-epibatidine from sigma2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]-epibatidine from dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-epibatidine from dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-epibatidine from dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of epibatidine-induced receptor activation at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as reduction in calcium flux preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-epibatidine from M2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641585(CHEMBL5571457)
Affinity DataIC50: 4.05E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed