BDBM50641587 CHEMBL5570620

SMILES CC1=CC[C@@H]2C[C@H]1[C@H](c1ccc(F)c(F)c1)NC2(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50641587   

TargetSigma intracellular receptor 2(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-epibatidine from sigma2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataIC50: 440nMAssay Description:Inhibition of epibatidine-induced receptor activation at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as reduction in calcium flux preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-epibatidine from alpha2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataIC50: 1.24E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641587(CHEMBL5570620)
Affinity DataIC50: 5.59E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed