BDBM50641738 CHEMBL5565486

SMILES CCOc1ncc2cc(-c3ccc4c(c3)N3CCCC3CO4)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641738   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Guizhou University

Curated by ChEMBL
LigandPNGBDBM50641738(CHEMBL5565486)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methione as substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Guizhou University

Curated by ChEMBL
LigandPNGBDBM50641738(CHEMBL5565486)
Affinity DataEC50:  360nMAssay Description:Induction of MAT2A degradation in human HCT-116 cells preincubated for 4 hrs followed by 1.0 MHz, 0.8W/cm2 ultrasound treatment for 0.5 mins by Weste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed